Urology

Light Micrograph of Section Through a Transitional Cell Carcinoma of the Bladder Wall

Advancing Science

Metabolic Enzymes Mark New Targets in Bladder Cancer

Key glycolytic enzymes acting as oncogenes may provide a novel path to overcoming cisplatin resistance.

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In a study of 199 patients who underwent gender-affirming robotic peritoneal flap vaginoplasty, 86% who completed one year or more of follow up were orgasmic, and the median time to achieve orgasm post-surgery was 180 days. Some previously anorgasmic patients also became newly orgasmic.

Surgical Innovation

Most Patients Achieve Orgasm in First Year After Gender-Affirming Vaginoplasty

Study finds 86 percent become orgasmic by one year after robotic peritoneal flap vaginoplasty, with more regaining ability after one year.
PYP scan

Complex Case Spotlight

A Successful Triple Transplant for Heart, Lungs, and Kidney

Thirteen-hour OR procedure entails a close partnership of transplant surgeons and specialists.
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Complex Case Spotlight

Challenges in Managing Small Renal Masses

A trio of cases demonstrate the need to carefully weigh diagnosis and treatment.
Four People Standing Around a Grill and Talking

Expert Perspectives

Prostate Cancer Screening: Can Community-Based Intervention Improve Engagement?

Researchers are testing a more proactive approach to address screening inequities.
All 36 men (38 ROIs) enrolled to the study with PI-RADS 4/5 ROI and no clinically significant prostate cancer (csPA) on initial biopsy underwent repeat MRI, following which 14 ROIs were downgraded while 24 ROIs remained suspicious. Of the 20 ROIs that underwent repeat biopsy, 30% were benign, 30% were Gleason grade group (GGG) 1, and 40% were GGG ≥ 2.

Advancing Science

Repeat Biopsy Helps Catch Cancer in Patients with Suspicious Prostate Lesions

Study suggests patients with PI-RADS 4 or 5 ROI with an initial negative biopsy should be promptly re-evaluated.

Complex Case Spotlight

The Uncertainty of Avoiding Radical Cystectomy

Case exemplifies the complex decisions faced by patients with high-risk NMIBC who elect bladder preservation.
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NYU Langone Health: A Leader in Urology

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Top 10

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Pioneers in MRI

to evaluate prostate cancer

Complex Case Spotlight

Challenges in Managing Small Renal Masses

CT Scan with Mass

Malignant Appearing Small Mass to Oncocytoma

For the first case, a healthy, 39-year-old man presented with abdominal pain, and a CT scan revealed a 2.2 centimeter enhancing solid mass (red circle). The man received a robotic partial nephrectomy. Upon pathology, the excised oncocytoma showed diffuse reactivity for the oncogenic marker CD117 and scattered positivity for CK7.

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CT Scan with Cyst

Benign Multi-Locular Cyst Appears as a Suspicious Malignant Cyst

In a second case, providers identified a mass in a healthy 54-year-old man: an incidental 2.5 centimeter complex cyst on chest CT (red circle) that was later confirmed via MRI as a 2.6 centimeter cystic left upper pole renal lesion. The septated mass had a thick rim and was rated Bosniak category III.

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CT Scan Showing Carcinoma

Comorbidity Considerations Essential

The third case involved a 59-year-old man with a history of cardiovascular conditions, including coronary artery disease, severe aortic regurgitation, a cerebrovascular accident, and a thoracic aortic aneurysm repair. He had a biopsy-proven, enlarging solid 2.2 centimeter papillary renal cell carcinoma (red circle). READ THE FULL ARTICLE

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